Table 1. Demographic and clinical features of the study population.
| Variable | Non-recurrent, n (%) | Recurrent, n (%) | P valuea |
|---|---|---|---|
| Age (years) | |||
| ≤57 | 28 (49) | 16 (59) | 0.385 |
| >57 | 29 (51) | 11 (41) | |
| Sex | |||
| Male | 36 (63) | 17 (63) | 0.986 |
| Female | 21 (37) | 10 (37) | |
| Race | |||
| White | 39 (68) | 16 (59) | 0.409 |
| Non-white | 18 (32) | 11 (41) | |
| Location | |||
| Cecum/transverse/descending colon | 19 (33) | 2 (7) | 0.029b |
| Ascending colon | 17 (30) | 10 (37) | |
| Sigmoid | 21 (37) | 15 (56) | |
| CEA (μg/L) | |||
| ≤5 | 52 (91) | 22 (82) | 0.279 |
| >5 | 5 (9) | 5 (19) | |
| Tumor stage | |||
| IIA | 6 (11) | 3 (11) | 0.191b |
| IIB, IIC | 2 (4) | 0 (0) | |
| IIIA | 4 (7) | 0 (0) | |
| IIIB | 33 (58) | 13 (48) | |
| IIIC | 12 (21) | 11 (41) | |
| Tumor differentiation | |||
| Moderate to well, well | 44 (77) | 22 (82) | 0.655 |
| Moderate to poor, poor | 13 (23) | 5 (19) | |
| Lymph vascular invasion | |||
| No | 45 (79) | 23 (85) | 0.497 |
| Yes | 12 (21) | 4 (15) | |
| Perineural invasion | |||
| No | 42 (74) | 19 (70) | 0.750 |
| Yes | 15 (26) | 8 (30) | |
| Margin positive | |||
| No | 23 (40) | 8 (30) | 0.342 |
| Yes | 34 (60) | 19 (70) | |
| Lymph nodes resected | |||
| 2-10 | 32 (56) | 15 (56) | 0.664 |
| 11-25 | 5 (9) | 1 (4) | |
| 25-65 | 20 (35) | 11 (41) | |
| Lymph nodes involved | |||
| 0 | 7 (12) | 3 (11) | 0.030 |
| 1-5 | 40 (70) | 12 (44) | |
| >5 | 10 (18) | 12 (44) | |
| Adjuvant chemotherapy | |||
| None or missing | 2 (4) | 3 (11) | 0.424 |
| FOLFOX | 47 (82) | 19 (70) | |
| Other | 8 (14) | 5 (19) | |
a
Two-sided Chi-square test.
b
Fisher's exact test.