Table 4. Logistic regression and ROC analyses of risk of tumor recurrence.
Variable | Non-recurrent n (%) | Recurrent n (%) | Logistic regression OR (95% CI) | P value | ROC, AUC (95% CI) | P value |
---|---|---|---|---|---|---|
miR-4772-3p | ||||||
<27.88 | 54 (95) | 16 (59) | 1.0 | |||
≥27.88 | 3 (5) | 11 (41) | 11.3 (2.38-53.2) | 0.002 | 0.72 (0.59-0.85) | 0.001 |
Tumor site | ||||||
Cecum/transverse/descending | 19 (33) | 2 (7) | 1.0 | |||
Ascending/sigmoid | 38 (67) | 25 (93) | 6.02 (1.14-31.8) | 0.034 | 0.63 (0.51-0.75) | 0.062 |
Lymph node positive | ||||||
≤5 | 47 (83) | 15 (56) | 1.0 | |||
>5 | 10 (17) | 12 (44) | 2.77 (0.84-9.17) | 0.095 | 0.65 (0.51-0.78) | 0.034 |
Mir-4772-3p was dichotomized using the 60th percentile of the ΔCT value of recurrence patients.
The variables mir-4772-3p expression, CEA level, and lymph node status were all included in the multivariate logistic regression model.
CEA and the AJCC stage were dropped due to insignificance.