Table 5. Analysis of time to recurrence and overall survival duration by Cox regression analysis.
| Variable | # of recurrences/# of patients | Time to recurrence (mean ± standard error)a | Risk of recurrence, HR (95% CI) | # of deaths/# of patients | Survival duration (mean ± standard error)a | Risk of death, HR (95% CI) |
|---|---|---|---|---|---|---|
| miR-4772-3p | ||||||
| <27.88 | 16/70 | 77.0±3.9 | 1.0 | 5/70 | 90.9±2.0 | 1.0 |
| ≥27.88 | 11/14 | 32.5±7.4 | 5.48 (2.49-12.1) | 4/14 | 60.9±5.3 | 6.19 (1.50-25.5) |
| P value | <0.001 | 0.012 | ||||
| Tumor site | ||||||
| Cecum/transverse/descending | 2/21 | 73.7±4.0 | 1.0 | 1/21 | 79.2±2.1 | 1.0 |
| Ascending/sigmoid | 25/63 | 62.1±6.0 | 7.42 (1.64-33.5) | 8/83 | 86.7±2.9 | 7.37 (0.74-73.3) |
| P value | <0.001 | 0.089 | ||||
| CEA (mg/L) | ||||||
| ≤5 | 22/74 | 70.3±4.4 | 1.0 | 5/74 | 90.6±2.1 | 1.0 |
| >5 | 5/10 | 43.2±8.8 | 2.87 (1.04-7.94) | 4/10 | 59.0±5.4 | 9.57 (2.29-39.9) |
| P value | 0.042 | 0.002 | ||||
a
Because median time to recurrence and overall survival duration could not be calculated for the low-risk groups, means and standard error values are presented for all groups.