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. 2016 Sep 1;7(46):76316–76326. doi: 10.18632/oncotarget.11783

Table 4. Multivariate analysis of Disease-free survival and Overall Survival.

Variables Hazard Ratio 95%CI Pa
LL UL
Disease-free survival
Age
 <65 Reference
 ≥65 1.90 1.27 2.83 .002b
TNM stage
 IB Reference
 II 1.82 0.76 4.37 .180
 III 3.15 1.28 7.72 .012b
N stage
 N0 Reference
 N1 0.90 0.48 1.71 .750
 N2 1.52 0.81 2.88 .194
 N3 2.36 1.28 4.36 .006b
Overall Survival
Regimens of therapy
 monotherapy Reference
 two-drug regimens 0.55 0.35 0.85 .008b
Age
 <65 Reference
 ≥65 2.14 1.39 3.28 .001b
Location of tumor
 cardia Reference
 corpus 0.45 0.20 1.02 .056
 antrum 0.54 0.34 0.86 .009b
Type of resection
 subtotal gastrectomy Reference
 total gastrectomy 2.39 1.31 4.39 .005b
N stage
 N0 Reference
 N1 0.86 0.43 1.72 .669
 N2 2.52 1.38 4.59 .003b
 N3 4.45 2.61 7.59 .000b

Abbreviations: N stage: Regional lymph nodes classification; LL =lower limit; UL=upper limit.

a

Cox regression analysis.

b

Statistically significance.