Table 4. Multivariate analysis of Disease-free survival and Overall Survival.
Variables | Hazard Ratio | 95%CI | Pa | |
---|---|---|---|---|
LL | UL | |||
Disease-free survival | ||||
Age | ||||
<65 | Reference | |||
≥65 | 1.90 | 1.27 | 2.83 | .002b |
TNM stage | ||||
IB | Reference | |||
II | 1.82 | 0.76 | 4.37 | .180 |
III | 3.15 | 1.28 | 7.72 | .012b |
N stage | ||||
N0 | Reference | |||
N1 | 0.90 | 0.48 | 1.71 | .750 |
N2 | 1.52 | 0.81 | 2.88 | .194 |
N3 | 2.36 | 1.28 | 4.36 | .006b |
Overall Survival | ||||
Regimens of therapy | ||||
monotherapy | Reference | |||
two-drug regimens | 0.55 | 0.35 | 0.85 | .008b |
Age | ||||
<65 | Reference | |||
≥65 | 2.14 | 1.39 | 3.28 | .001b |
Location of tumor | ||||
cardia | Reference | |||
corpus | 0.45 | 0.20 | 1.02 | .056 |
antrum | 0.54 | 0.34 | 0.86 | .009b |
Type of resection | ||||
subtotal gastrectomy | Reference | |||
total gastrectomy | 2.39 | 1.31 | 4.39 | .005b |
N stage | ||||
N0 | Reference | |||
N1 | 0.86 | 0.43 | 1.72 | .669 |
N2 | 2.52 | 1.38 | 4.59 | .003b |
N3 | 4.45 | 2.61 | 7.59 | .000b |
Abbreviations: N stage: Regional lymph nodes classification; LL =lower limit; UL=upper limit.
Cox regression analysis.
Statistically significance.