Table 1.
Inter-group comparisons of macular thickness (micron) and electroretinogram (ERG) amplitude (Mvolt) from baseline to 6 months in the treatment (saffron) and control (placebo) groups of patients with dry and wet age-related macular degeneration (AMD).
| Dry AMD | Wet AMD | |||||||
|---|---|---|---|---|---|---|---|---|
| Baseline | 3 months | 6 months | P value* | Baseline | 3 months | 6 months | P value * | |
| Macular thickness | 0.58 | 0.12 | ||||||
| Saffron group | 227.92 ± 31.5 | 228 ± 28.3 | 225.64 ± 30.3 | 371.83 ± 41.3 | 283.87 ± 4.3 | 269.25 ± 3.7 | ||
| Placebo group | 239.87 ± 37.4 | 231.6 ± 24.6 | 238.54 ± 22.3 | 381.55 ± 48.5 | 291.33 ± 4.9 | 228.47 ± 8.9 | ||
| P value ** | 0.32 | 0.58 | 0.28 | 0.49 | 0.84 | 0.05 | ||
| ERG amplitude | 0.05 | 0.21 | ||||||
| Saffron group | 100.68±31.3 | 102.14 ± 3.1 | 102.9 ± 3.1 | 80.45 ± 3.5 | 80.97 ± 0.27 | 81.53 ± 2.8 | ||
| Placebo group | 85.88 ± 35.4 | 89.8 ± 3.5 | 89.6 ± 3.5 | 76.38 ± 2.1 | 79.92 ± 0.21 | 79.42 ± 2.1 | ||
| P value ** | 0.20 | 0.03 | 0.12 | 0.63 | 0.007 | 0.26 | ||
*
P value for the effect of time in the repeated measures analysis of variance;
**
P value for group comparisons with independent t-tests.