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Corticosterone reduced croton oil-induced swelling in mouse ears in a dose-dependent manner at 6 and 24 h in a model of irritant dermatitis. Reduction in inflammatory swelling by increasing dose (μg) of corticosterone after (a) 6 and (b) 24 h of treatment with croton oil (6 h, n = 4/group; 24 h, n = 8–12/group). Data are mean ± SEM. Corticosterone was applied to mouse ears in a volume of 10 μL vehicle.
