Fig. 7.

Corticosterone (B) affected gene transcripts in sponges to a greater degree than 5α-tetrahydrocorticosterone (5αTHB). Real-time PCR analysis of transcripts of (a) vascular, (b) inflammatory and (c) extra-cellular matrix (ECM) genes in sponges containing either vehicle (V), B 3 mg or 5αTHB 3 and 15 mg as indicated. Data (mean ± SEM) were analysed with one-way ANOVA followed by Tukey’s post hoc test; n = 8–12 mice/group; p ⩽ 0.05, # = vs V, ^* = vs B, £ = 5αTHB 3 mg vs 15 mg.