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. Author manuscript; available in PMC: 2018 Mar 1.
Published in final edited form as: Small. 2016 Dec 27;13(10):10.1002/smll.201603121. doi: 10.1002/smll.201603121

Figure 3.

Figure 3

THP-1 cellular uptake of nanoparticles. (A) Confocal images of MTP-BPLP-PLA-PLX4032 nanoparticles taken up and internalized by THP-1 cells. Nuclei were stained by DAPI; nanoparticles were shown in the FITC and PE-Texas Red channels, CD11b was immunostained by Alexa647 (pseudo color in pink). (B) FACS analysis of THP-1 cells before and after treated with BPLP-PLA-PLX4032 and MTP-BPLP-PLA-PLX4032 nanoparticles (C) FITC and PE-Texas Red average fluorescence intensity of THP-1 cells, THP-1 cells with BPLP-PLA-PLX4032 and MTP-BPLP-PLA-PLX4032 nanoparticles. *, p<0.01 compare to the THP-1 control. (D) THP-1 cell binding efficiency as the percentage of THP-1 cells that were labeled by BPLP-PLA-PLX4032 and MTP-BPLP-PLA-PLX4032 nanoparticles. *, p<0.01.