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. Author manuscript; available in PMC: 2018 Mar 7.
Published in final edited form as: Cell Metab. 2017 Feb 9;25(3):727–738. doi: 10.1016/j.cmet.2017.01.005

Figure 6. Changes in Human β Cells in Culture with Allogeneic Lymphoid Cells from Patients with T1D.

Figure 6

PBMCs from patients with T1D or healthy control subjects (HC) were cultured with human islets for 4 days. Single β cell composition was analyzed by FACS after staining with FluoZin and TMRE. Representative data showing SSC/FSC from one of four experiments are shown. The numbers indicate the percentage of Top and Btm β cells (A). (B) The percentage of Btm β cells from each well from four independent experiments was calculated and compared. Each data point represents a pool of islet cells from four separate experiments (mean ± SEM; ****p = 0.0001, Dunnett’s multiple comparison test).