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. Author manuscript; available in PMC: 2018 Mar 7.
Published in final edited form as: Structure. 2017 Feb 2;25(3):434–445. doi: 10.1016/j.str.2017.01.006

Figure 5. 4-stage scheme for integrative structure determination of Pom152FL.

Figure 5

The integrative structure determination of Pom152FL proceeds through 4 stages: (1) gathering data, (2) representing and translating data into spatial restraints, (3) conformational sampling to produce an ensemble of structures that satisfies the restraints, and (4) analyzing, assessing, and validating the ensemble structures. The modeling protocol (i.e., stages 2, 3, and 4) was scripted using the Python Modeling Interface (PMI), version 4d97507, a library for modeling macromolecular complexes based on our open-source Integrative Modeling Platform (IMP) package, version 2.6 (http://integrativemodeling.org) (Russel et al., 2012).