Table 1.
Sample Measures
| Variable | 22q | ND | p | d |
|---|---|---|---|---|
| N | 150 | 150 | - | - |
| Mean Age (yrs ± SD) | 15.3 ± 4.2 | 16.0 ± 3.6 | N.S. | −0.16 |
| Psychosis Spectrum (%) | 94 (63%) | 94 (63%) | - | - |
| Psychosis-Prone | 83 (55%) | 85 (57%) | N.S. | - |
| Psychosis | 11 (7%) | 9 (6%) | N.S. | - |
| Mean Onset (yrs ± SD) | 11.0 ± 4.0 | 12.1 ± 3.2 | N.S. | −0.31 |
| SIPS Total (score ± SD) | 20.3 ± 13.9 | 14.7 ± 10.9 | <0.01 | 0.45 |
| GAF (score ± SD) | 62.8 ± 14.4 | 70.0 ± 14.5 | <0.001 | −0.50 |
| Sex | ||||
| Male (%) | 92 (61%) | 84 (56%) | N.S. | - |
| Female (%) | 58 (39%) | 66 (44%) | N.S. | - |
| Race | <0.001 | - | ||
| Caucasian (%) | 130 (87%) | 52 (35%) | <0.001 | - |
| African American (%) | 11 (7%) | 81 (54%) | <0.001 | - |
| Mixed (%) | 6 (4%) | 16 (11%) | N.S. | - |
| Asian (%) | 2 (1%) | 1 (1%) | N.S. | - |
| Other (%) | 1 (1%) | 0 (0%) | N.S. | - |
| Reading Proficiency (±SD) | 89.2 ± 13.5 | 100.5 ± 15.4 | <0.001 | −0.78 |
| Education (yrs ± SD) | ||||
| Proband | 7.9 ± 3.6 | 9.2 ± 3.4 | <0.05 | −0.38 |
| Mother | 14.8 ± 2.3 | 14.3 ± 2.4 | N.S. | −0.21 |
| Estimated Income (±SD) | 75,030 ± 31,053 | 51,848 ± 28,415 | <0.001 | 0.78 |
Note: 22q11DS=22q11.2 deletion syndrome; ND=non-deleted; SOPS=scale of prodromal symptoms; GAF=global assessment of function; SD=standard deviation; Yrs=years; d=Cohen's d for effect size; N.S.=non-significant. Mean age, mean age of onset, SOPS total, GAF, reading proficiency, and education were compared using Student's t-test. Proportions of psychosis spectrum, sex, and race were compared using Fisher's exact test. All comparisons were two-sided with significance threshold of p=0.05.