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. 2017 Mar 9;8:262. doi: 10.3389/fimmu.2017.00262

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Copyright © 2017 Maloupazoa Siawaya, Mveang-Nzoghe, Mvoundza Ndjindji, Mintsa Ndong, Essone and Djoba Siawaya.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Photomicrographs of nitroblue tetrazolium (NBT) dye reduction profiles of selected HIV-exposed uninfected (HEU) infants blood neutrophils (at ×100 magnification). Reactive oxygen species (ROS)⁻ HEU infants indicate infants with impaired ROS production. ROS⁺ HEU infants indicate infants with normal ROS production. ROS⁺ HEU infants illustrated by HEU 17, 16, and 27 showed increased formazan deposits visible as a large dark purple to black intra-cytoplasmic inclusions whereas, ROS⁻ HEU infants illustrated by HEU 8, 9, and 22 showed few or no formazan deposits.