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. 2017 Mar 9;8:251. doi: 10.3389/fimmu.2017.00251

Figure 7.

Figure 7

Interferon-I receptor (IFNAR) deficiency does not provide conventional dendritic cell (cDC) subsets with an inherent retention benefit. (A) Total splenocytes from mock- and murine cytomegalovirus (MCMV)-infected BM chimeras were analyzed without distinguishing between CD45.1 or CD45.2 expression. Concatenated flow plots show analysis of dendritic cell (DC) (above) and cDC subsets (below). Cell numbers for each population are quantified in the graphs. (B–D) cDC subsets from the mixed chimeras in (A) were separated into IFNAR-KO (45.2) and -WT (45.1) populations and analyzed side by side. Concatenated flow plots show the separation and relative frequency of KO versus WT cells for each subset from mock- (PBS) and MCMV-infected mixed chimeras. Cell numbers for each population are quantified in the graphs. Numbers on flow plots denote frequency of parent population. All graphs show data for individual mice (dots) and group means (bars). Results are representative of at least two experiments.