Table 2.
Univariate Cox proportional hazards model results for all patients.
| Parameter* | HR | HR 95%CI | p-Value | |
|---|---|---|---|---|
| Karnofsky Performance status | 0.0003 | |||
| 90–100 | 0.681 | 0.457 | 1.014 | 0.0587 |
| 70–80 | 0.379 | 0.237 | 0.607 | <0.0001 |
| Recursive partitioning analysis | 0.0143 | |||
| 1 | 0.565 | 0.348 | 0.919 | 0.0214 |
| 2 | 0.581 | 0.394 | 0.857 | 0.0062 |
| Primary location | 0.5579 | |||
| Breast | 1.250 | 0.691 | 2.259 | 0.4603 |
| Lung | 1.282 | 0.866 | 1.899 | 0.2149 |
| Melanoma | 1.460 | 0.778 | 2.740 | 0.2390 |
| Gender | ||||
| Female | 0.931 | 0.669 | 1.297 | 0.6739 |
| Age | ||||
| ≤65 | 1.090 | 0.776 | 1.533 | 0.6185 |
| Brain metastatic event | ||||
| First brain metastatic event | 1.014 | 0.730 | 1.408 | 0.9333 |
| Initial metastasis | ||||
| Brain | 1.070 | 0.763 | 1.500 | 0.6953 |
| Extracranial metastases | ||||
| Present | 0.930 | 0.664 | 1.303 | 0.6723 |
| Number of metastases | ||||
| 1 or 2 | 1.196 | 0.828 | 1.729 | 0.3402 |
*Reference groups: KPS ≤ 70, RPA = 3, primary location = others, gender = male, age > 65, brain metastatic event = SBME, extracranial metastases = absent, initial met = others, number of metastases = 3 or more.