Table 3.

Summary of outcome data for meta-analyses

Study	Study population	Comparator to liver biopsy	Correlation test	Liver fibrosis stage	Sensitivity (%)	Specificity (%)
Sporea et al. [34]	C	VTq	Spearman rho = 0.65 (p < 0.001)	F ≥ 1	69.9	80
				F ≥ 2	69.1	79.8
				F ≥ 3	74.8	81.5
				F4	84.3	76.3
Friedrich-Rust et al. [32]	B	VTq	Spearman rho = 0.42 (p < 0.001)	F ≥ 2	50	90
		TE	Spearman rho = 0.56 (p < 0.001)	Not available	Not available	Not available
Friedrich-Rust et al. [33]	C	VTq	Not available	Not available	Not available	Not available
Yamada et al. [39]	C	VTq	Pearson rho = 0.76 (p < 0.001)	F ≥ 2	92.5	76.2
				F ≥ 3	84.6	87.8
Nishikawa et al. [42]	C	VTq	Spearman rho = 0.73 (p < 0.001)	F ≥ 1	69.1	85.7
				F ≥ 2	81.8	87.1
				F ≥ 3	88.9	82.5
				F4	85.7	86.2
Chen et al. [40]	C	VTq	Spearman rho = 0.70 (p < 0.001)	F ≥ 2	74.1	87
				F ≥ 3	90.2	89.5
				F4	88.9	79.8
Rizzo et al. [43]	C	VTq	Not available	F ≥ 2	81	70
				F ≥ 3	91	86
				F4	83	86
		TE	Not available	F ≥ 2	71	71
				F ≥ 3	77	85
				F4	70	82
Kuroda et al. [41]	C	VTq	Spearman rho = 0.98 (p = 0.002)	Not available	Not available	Not available
Ye et al. [44]	B	VTq	Spearman rho = 0.87 (p < 0.001)	Not available	Not available	Not available
Liu et al. [38]	B	VTq	Spearman rho = 0.85 (p < 0.001)	F ≥ 2	83.95	83.05
				F4	93.1	76.83
		TE	Spearman rho = 0.81 (p < 0.001)	F ≥ 2	81.8	71.24
				F4	88.1	86.67

TE transient elastography, VTq Virtual Touch™ Quantification