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. 2017 Mar 9;16:22. doi: 10.1186/s12940-017-0234-4

Table 3.

Associations between occupational groups and blood pressure in different mtDNA function groupsa

mtDNA function group
(D-loop)b
mtDNA function group
(MT-TF) c
Low High Low High
Outcome N Beta (95% CI) p N Beta (95% CI) p N Beta (95% CI) p N Beta (95% CI) p
Systolic blood pressure 100 11.32 (6.61, 15.91) <0.001 106 3.34 (−1.18, 7.85) 0.15 107 12.31 (7.93, 16.69) <0.001 108 1.11 (−3.51, 5.73) 0.63
Diastolic blood pressure 100 3.53 (0.18, 6.88) 0.039 106 3.64 (0.28, 7.00) 0.034 107 3.00 (−0.38, 6.38) 0.081 108 2.39 (−0.96, 5.73) 0.16

aThe model included age, BMI, family history of cardiovascular disease, smoking history, and current residence as adjustments

bDerived from unmethylated D-loop and relative mtDNA copy number. Two groups stratified by median

cDerived from unmethylated MT-TF and relative mtDNA copy number. Two groups stratified by median