Table 3.
mtDNA function group (D-loop)b |
mtDNA function group (MT-TF) c |
|||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Low | High | Low | High | |||||||||
Outcome | N | Beta (95% CI) | p | N | Beta (95% CI) | p | N | Beta (95% CI) | p | N | Beta (95% CI) | p |
Systolic blood pressure | 100 | 11.32 (6.61, 15.91) | <0.001 | 106 | 3.34 (−1.18, 7.85) | 0.15 | 107 | 12.31 (7.93, 16.69) | <0.001 | 108 | 1.11 (−3.51, 5.73) | 0.63 |
Diastolic blood pressure | 100 | 3.53 (0.18, 6.88) | 0.039 | 106 | 3.64 (0.28, 7.00) | 0.034 | 107 | 3.00 (−0.38, 6.38) | 0.081 | 108 | 2.39 (−0.96, 5.73) | 0.16 |
aThe model included age, BMI, family history of cardiovascular disease, smoking history, and current residence as adjustments
bDerived from unmethylated D-loop and relative mtDNA copy number. Two groups stratified by median
cDerived from unmethylated MT-TF and relative mtDNA copy number. Two groups stratified by median