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(A) MRI LV/TL (left) and ex vivo LV/TL (right) ratios at 27 and 28 weeks, respectively, in transgenic mice overexpressing the beta3 adrenergic receptor and immunized (TG AdrB1+) or not (TG CTL) against AdrB1-ECII, and their wild-type littermates with (WT AdrB1+) or without (WT CTL) immunization. Systolic (B) and diastolic (C) indexes determined in the same animals after 10, 18 and 27 weeks, *P ≤ 0.0.05; **P ≤ 0.0.01 as indicated.
