Table 2. Genomic networks with altered methylation in MTLE.

Pathway list	Pathway term	# DMS involved	% to total DMS	Genes	P Value	Fold Enriched
#1	hsa00591:Linoleic acid metabolism	4	2.5974	CYP3A43, CYP3A4, ALOX15, CYP2C9	0.0017	16.1429
#2	hsa00983:Drug metabolism	4	2.5974	CYP3A43, CYP3A4, NAT2, UGT2A3	0.0059	10.5116
#3	hsa00830:Retinol metabolism	4	2.5974	CYP3A43, CYP3A4, CYP2C9, UGT2A3	0.0110	8.3704
#4	hsa00980:Metabolism of xenobiotics by cytochrome P450	4	2.5974	CYP3A43, CYP3A4, CYP2C9, UGT2A3	0.0147	7.5333
#5	hsa00982:Drug metabolism	4	2.5974	CYP3A43, CYP3A4, CYP2C9, UGT2A3	0.0160	7.2903
#6	hsa00140:Steroid hormone biosynthesis	3	1.9481	CYP3A43, CYP3A4, UGT2A3	0.0596	7.3696