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. 2017 Mar 9;7:44141. doi: 10.1038/srep44141

Figure 1. Volcano plot of the miRNA profiles of BMDMs infected with La-WT and La-arg− L. (L.) amazonensis.

Figure 1

Each dot represents one miRNA of BMDMs infected for 4, 12, 24 and 48 h with La-WT or La-arg− L. (L.) amazonensis. The red dot indicated up-regulated miRNA and green dot indicated down-regulated miRNAs. Blue dotted line corresponds to p = 0.05, log 10. The relative up- and down-regulation of miRNAs, expressed as boundaries of 2 or −2 of Fold Regulation, respectively. P-value was determined based on two-tailed Student’s t test. The data are representative of three independent experiments.