Table 1. Ten genes present in the highest number of gene sets most significantly enriched in hypertension in thoracic aorta and mesenteric arteries and their expression fold change in hypertensive mice as compared to normotensive mice.
Thoracic aorta |
Mesenteric arteries |
||||||
---|---|---|---|---|---|---|---|
Gene | Number of gene sets (out of 68) | log2FC | Expression change–FDR adj. p value | Gene | Number of gene sets (out of 36) | log2FC | Expression change–FDR adj. p value |
Cdh13 | 30 | 0.595 | 0.0005 | Igfbp3 | 9 | 0.17 | 0.11 |
Sphk1 | 29 | 1.221 | 0.0003 | Eif5a | 9 | 0.15 | 0.24 |
Sod1 | 29 | 0.191 | 0.0391 | Inhba | 8 | 0.19 | 0.39 |
Thy1 | 28 | 0.794 | 0.0013 | Mast2 | 8 | 0.17 | 0.07 |
Tgfb1 | 22 | 0.284 | 0.0248 | Cdc23 | 7 | 0.06 | 0.49 |
Nme2 | 21 | 0.283 | 0.0092 | Ccdc88a | 7 | 0.10 | 0.28 |
Col4a3 | 21 | 0.245 | 0.0278 | Sphk1 | 7 | 0.40 | 0.04 |
Vegfa | 20 | 0.330 | 0.0594 | Apbb1 | 7 | 0.17 | 0.23 |
Angptl4 | 19 | 0.402 | 0.0426 | Anapc5 | 7 | 0.18 | 0.17 |
Htatip2 | 18 | 0.835 | 0.0002 | Ppp5c | 6 | 0.09 | 0.41 |
log2FC = logarithm of Fold Change (hypertensive vs. normotensive mice).