Table 5.

Detailed description of 13 pregnancies with adverse outcome and cytopenia during pregnancy

Pregnancy	Cytopenia category	Timing of cytopenia	SLE medications during pregnancy	Other manifestations during pregnancy	Adverse outcome
A*	Leukopenia	Continued from 6 months pre- conception	HCQ (newly started)		pre-eclampsia, emergent pre- term delivery at 31 weeks
B#	Thrombocytopenia	Continued from 6 months pre- conception	HCQ (continued), prednisone 30mg (continued)		pre-term at 33 weeks
C**	Leukopenia	Continued from 6 months pre- conception	HCQ (continued), AZA (continued), prednisone 20mg before conception → 40mg		pre-term at 36 weeks
D#	Thrombocytopenia	Continued from 6 months pre- conception	HCQ (continued), prednisone 20mg due to ITP		pre-term at 36 weeks
E	Thrombocytopenia, Leukopenia	Continued from 6 months pre- conception	HCQ (continued), prednisone 20mg (newly started)		stillbirth at 32 weeks
F	Thrombocytopenia, Hemolytic anemia	Started in 1st trimester	Prednisone 60mg (new in 1st trimester), tapered to 20mg		pre-term at 31 weeks
G*	Leukopenia	Started in 1st trimester	HCQ (newly started)		pre-term at 30 weeks
H	Leukopenia	Started in 1st trimester	HCQ (continued), AZA (continued), prednsione 7.5mg (continued)		pre-term at 33 weeks
I	Leukopenia	Started in 1st trimester	None		miscarriage at 16 weeks
J	Leukopenia	Started in 1st trimester	AZA (newly started), prednisone 60mg (newly started)	New-onset Class III lupus nephritis, arthritis, skin disease	pre-term at 34 weeks
K**	Leukopenia	Started in 2nd trimester	HCQ (continued), AZA (continued), prednisone 15mg before conception → 60mg	Pleuritis, skin disease	pre-term at 33 weeks
L	Thrombocytopenia	Started in 2nd trimester	Prednisone 10mg at conception → 60mg		stillbirth at 28 weeks
M	Thrombocytopenia	Started in 3rd trimester	HCQ (continued), aspirin (newly started)		pre-term at 36 weeks

Pregnancies carried by the same woman are indicated by * or # or **

Leukopenia: WBC <4000/mm³ not attributed to medication. Thrombocytopenia: platelet count <100×10⁹/L

Cell counts presented in thousands per cubic millimeter. HCQ: hydroxychloroquine. AZA: azathioprine.