TABLE 2—
Variable | None (n = 4153) | 1–9 Days (n = 573) | 10–19 Days (n = 148) | ≥ 20 Days (n = 239) | P for Trend |
Total cardiovascular disease | |||||
No. of events | 156 | 34 | 11 | 14 | |
Event ratea | 1.44 | 2.43 | 2.98 | 2.46 | |
AHR (95% CI)b | 1 (Ref) | 1.05 (0.69, 1.50) | 1.36 (0.60, 3.09) | 0.88 (0.42, 1.82) | .78 |
Stroke or transient ischemic attack | |||||
No. of events | 43 | 10 | 5 | 4 | |
Event ratea | 0.39 | 0.73 | 1.38 | 0.67 | |
AHR (95% CI)b | 1 (Ref) | 1.25 (0.51, 3.07) | 2.77 (0.83, 9.24) | 1.03 (0.22, 4.78) | .69 |
Coronary heart disease | |||||
No. of events | 78 | 14 | 5 | 8 | |
Event ratea | 0.72 | 0.96 | 1.46 | 1.43 | |
AHR (95% CI)b | 1 (Ref) | 0.85 (0.40, 1.79) | 1.30 (0.43, 3.95) | 1.01 (0.38, 2.65) | .97 |
Cardiovascular disease mortality | |||||
No. of events | 30 | 12 | 4 | 5 | |
Event ratea | 0.27 | 0.84 | 1.04 | 0.87 | |
AHR (95% CI)b | 1 (Ref) | 1.60 (0.67, 3.85) | 1.91 (0.55, 6.61) | 1.20 (0.23, 6.16) | .84 |
Note. AHR = adjusted hazard ratio; CARDIA = the Coronary Artery Risk Development in Young Adults study; CI = confidence interval. The sample size was n = 5113. We assessed the number of participants who used marijuana over the last 30 d during the examination immediately before the date of the clinical cardiovascular event, date of death, or the last date of contact.
Per 1000 person-years.
Adjusted for age, gender, race, educational attainment, and study center as well as family history of cardiovascular disease and time-varying physical activity, body mass index, high blood pressure, diabetes, dyslipidemia, depression, smoking (pack-years), cumulative alcohol use, cumulative binge drinking episodes, and cumulative use of other illicit drugs (cocaine, crack, speed, methamphetamine, or opioids).