Table 3.
1 year overall survival and treatment-related mortality by multivariate analysis in patients with HC
OS | TRM | ||||
---|---|---|---|---|---|
Parameter | Class | Hazard Ratio CI 95% |
P-value | Hazard Ratio CI 95% |
P-value |
HC Group | Control | 1.00 | 0.14 | 1.00 | |
Grade I-II | 0.76 (0.52-1.11) | 0.91 (0.59-1.42) | 0.69 | ||
Grade III-IV | 1.20 (0.90-1.61) | 1.52 (1.10-2.10) | 0.01 | ||
Graft source | M BM/PBSC | 1.00 | <0.01 | 1.00 | |
MM BM/PBSC | 2.60 (1.90-3.55) | 2.28 (1.53-3.41) | <0.01 | ||
M UCB | 1.14 (0.77-1.68) | 1.34 (0.85-2.12) | 0.21 | ||
MM UCB | 1.53 (1.25-1.89) | 1.43 (1.10-1.87) | 0.01 |
Covariates tested in UVA were: ATG, sex, age, disease risk, conditioning regimen intensity
Abbreviations:BM, bone marrow; CMV, cytomegalovirus; HC, hemorrhagic cystitis; M, matched; MM, mismatched; PBSC, peripheral blood stem cell; UCB, umbilical cord blood.