Table 3.
Means and standard deviations of peak subjective effects ratings
| Placebo | 125 mg/70 kg | 250 mg/70 kg | ||
|---|---|---|---|---|
| Any drug effect | 0.25 (0.45) | 2.25 (0.87)*** | 3.42 (0.79) *** | +++ |
| A rush | 0.17 (0.39) | 2.42 (0.90) *** | 3.33 (0.98) *** | ++ |
| Any good effects | 0.25 (0.45) | 2.42 (0.90) *** | 3.33 (0.78) *** | ++ |
| Any bad effects | 0.25 (0.45) | 0.75 (0.87) | 1.75 (1.42) ** | + |
| Any effects that you like | 0.25 (0.45) | 2.33 (0.98) *** | 3.33 (0.78) *** | ++ |
| High | 0.08 (0.29) | 2.25 (0.87) *** | 3.42 (0.79) *** | +++ |
| Drowsy/sleepy | 0.33 (0.89) | 0.67 (0.78) | 1.08 (1.24) | |
| Alert/energetic | 0.25 (0.62) | 2.58 (1.08) *** | 3.50 (0.90) *** | |
| Jittery | 0.25 (0.45) | 2.08 (1.08) *** | 2.75 (1.29) *** | |
| Calm/relaxed | 0.58 (1.16) | 1.33 (0.98) | 1.92 (1.08) * | + |
| Stimulated | 0.42 (0.67) | 2.50 (1.00) *** | 3.58 (0.79) *** | ++ |
| Sexual desire | 12.08 (15.69) | 50.42 (31.08) ** | 63.42 (32.19) *** | + |
Note. With the exception of sexual desire, participants rated items on a scale ranging from 0–4 (0 = Not at all, 1 = Possibly mild, but not sure, 2 = Definitely mild, 3 = Moderately, 4 = Strongly). Sexual desire was rated using a visual analog scale ranging from 0 to 100 (“None” and “Intense,” respectively). Peak subjective effects were calculated using the maximum value observed over the time course for each participant. Peak subjective effects were compared using repeated measures ANOVA with a within subjects factor of dose (three levels), and simple effects (based on the F statistic) contrasts comparing each dose.
Ratings at 125 and 250 mg/70 kg that are significantly different from placebo are indicated with
as p < .05,
as p < .01, and
as p < .001.
Ratings at which 125 and 250 mg/70 kg are significantly different are indicated with
as p < .05,
as p < .01, and
as p < .001. For comparisons between 250 mg/70kg and placebo, Cohen’s d ranged across measures from 0.64 to 4.80. For comparisons between 125 mg/70 kg and placebo, Cohen’s d ranged from 0.35 to 2.94. For comparisons between 250 and 125 mg/70 kg, Cohen’s d ranged from 0.37 to 1.64.