Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Jan 26;18(2):251. doi: 10.3390/ijms18020251

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2017 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Effects of Mt1 overexpression on Zn and Cu levels. Total hippocampal (top) and cortical (bottom) homogenates from young (~6 months) and old (~14 months) mice were analyzed by ICP-MS. In the hippocampus, copper and zinc levels were increased and decreased by aging, respectively; both metals were increased in the cortex. APP and Mt1 expression showed different effects depending on the metal and brain area. Results are mean ± SEM (n = 7–11); ▲ p at least ≤0.05 vs. APP negative mice. ♠ p < 0.05 interaction between APP and TgMT.