Table 2.
Total number of spleen cells and amounts of human CD45+ immune cells in PBMC-engrafted mice.
| HC | HC + Treg | MS | MS + Treg | DMF | DMF + Treg | |
|---|---|---|---|---|---|---|
| spleen cells ×106 | 52.41 ± 14.34 | 32.09 ± 4.85 | 41.67 ± 6.47 | 34.70 ± 9.95 | 57.38 ± 10.09 | 59.75 ± 9.65 |
| huCD45+ cells in % | 5.77 ± 3.89 | 1.77 ± 0.28 | 3.87 ± 0.52 | 2.80 ± 0.86 | 7.41 ± 3.06 | 0.79 ± 0.15 |
Mice transferred with human PBMC ± Treg were sacrificed on day eight. Number of spleen cells was determined and ratios of human CD45+ immune cells were analyzed by flow cytometry. Data are displayed as mean values ± SEM of n = 5 mice per group.