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. 2017 Jan 27;18(2):275. doi: 10.3390/ijms18020275

Figure 6.

Figure 6

Effects of ID extract on inhibition of MDA-MB-231 breast cancer tumor growth and induction of apoptosis. Mice received an injection of MDA-MB-231 cells and were divided into three groups. ID extract was administered orally five times per week. On day 22, mice were sacrificed and the tumors were excised; (A) Body weight curves of MDA-MB-231 cell-bearing mice; (B) The tumor volume curves of MDA-MB-231 cell-bearing mice; (C) The tumor weight bars of MDA-MB-231-bearing mice; (D) Tumor tissues were analyzed by terminal deoxyribonucleotide transferase-mediated dUTP nick end-labeling (TUNEL) assay. Paraffin-embedded tumors were sectioned to a thickness of 5 µm. The slides were examined under a microscope and photographed (200×). Indicated bar is 10 µm; (E) Apoptotic body number of MDA-MB-231 tumor presented as percentages. The results are expressed as the mean ± SD. * p < 0.05. ID: Ixeris dentata.