Figure 1.

Two examples of staining patterns for EphA2 and EphB4 in sets of tumor and normal tissue from patients with colon cancer. (A) shows the most generally found pattern, with low expression of both proteins in normal tissue and abundant expression in tumor tissue; (B) shows an aberrant expression pattern (as indicated in Figure 2), with extremely high EphA2 expression in normal tissue and absence of staining in the corresponding tumor tissue. The scale bars represent 150 micrometers; (C) shows 40× enlargements of the sections indicated in A. Red arrows indicate membranous staining. The scale bar represents 30 micrometer.