Table 1.

Characteristics of inhaled First Generation Antipsychotic (FGA) loxapine.

Route of Administration	Inhalatory
Half Life	6–8 h
Time to peak concentration	2 min
Preparation instructions	Inhalation powder. 10 mg unit in a single-use inhaler
Food and Drug Administration (FDA) Indications	Acute treatment of agitation associated with schizophrenia or bipolar I disorder in adults
Available Dosage	10 mg
Maximum Dosage	10 mg/24 h
Average dose for tranquillization	10 mg/24 h
Recommendations	Administration requires a somewhat, partial or fully cooperative patient. Contraindicated in patients with diagnosis or history of asthma, Chronic Obstructive Pulmonary Disease (COPD), other lung disease associated with bronchospasm or in patients with acute respiratory symptoms or signs and with current use of medications to treat airways disease. It is not approved for the treatment of patients with dementia-related psychosis
Costs	$174/dose in USA (EUR price not yet available)