| NSCLC | Non-small-cell lung cancer |
| SCLC | Small-cell lung cancer |
| mTOR | mammalian target of rapamycin |
| mTORC1 | mTOR complex 1 |
| mTORC2 | mTOR complex 2 |
| BID | BH3 interacting-domain death agonist |
| Bik | Bcl-2-interacting killer |
| Noxa | Phorbol-12-myristate-13-acetate-induced protein 1 |
| HRK | Activator of apoptosis harakiri |
| PUMA | BCL2 Binding Component 3 |
| Bax | BCL2 Associated X |
| Bak | Bcl-2 homologous antagonist/killer |
| Bim | BCL2-Like 11 |
| Bcl-2 | B-cell lymphoma 2 |
| Bfl-1 | BCL2 Related Protein A1 |
| MCL-1 | Myeloid Cell Leukemia Sequence 1 |
| Fas | Tumor Necrosis Factor Receptor Superfamily, Member 6 |
| RTK | Receptor tyrosine kinase |
| PI3K | Phosphatidylinositol-3 kinase |
| TNFα | Tumor necrosis factor alpha |
| TNFR1 | TNFα Receptor 1 |
| TRADD | TNFR1-associated death domain |
| TRAIL | TNF-related apoptosis inducing ligand |
| FADD | Fas-associated protein with death domain |
| NF-κB | Nuclear factor kappa-light-chain-enhancer of activated B cells |
| MDM2 | Mouse double minute 2 homolog |
| MOMP | Mitochondrial outer membrane permeabilization |
| ER stress | Endoplasmic reticulum stress |
| DISC | Death-inducing signaling complex |
| FIP200 | FAK family kinase-interacting protein of 200 kDa |
| ULK1 | UNC-51-like kinase 1 |
| IGF-1 | Insulin-like growth factor-1 |
| HER | Human epidermal growth factor receptor |
| VEGFRs | Vascular endothelial growth factor receptors |
| IRS | Insulin receptor substrate |
| PtdIns(4,5)P2 | Phosphatidylinositol 4,5-bisphosphate |
| PtdIns(3,4,5)P3 | Phosphatidylinositol (3,4,5)-trisphosphate |
| PtdIns(3,4)P2 | Phosphatidylinositol 3,4-bisphosphate |
| PTEN | Phosphatase and tensin homolog |
| PDK1 | 3-Phosphoinositide-dependent protein kinase-1 |
| PP2A | Protein phosphatase 2 |
| LKB1 | Liver kinase B1 |
| ERAD | Endoplasmic-reticulum-associated protein degradation |