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. 2017 Feb 10;18(2):367. doi: 10.3390/ijms18020367
NSCLC Non-small-cell lung cancer
SCLC Small-cell lung cancer
mTOR mammalian target of rapamycin
mTORC1 mTOR complex 1
mTORC2 mTOR complex 2
BID BH3 interacting-domain death agonist
Bik Bcl-2-interacting killer
Noxa Phorbol-12-myristate-13-acetate-induced protein 1
HRK Activator of apoptosis harakiri
PUMA BCL2 Binding Component 3
Bax BCL2 Associated X
Bak Bcl-2 homologous antagonist/killer
Bim BCL2-Like 11
Bcl-2 B-cell lymphoma 2
Bfl-1 BCL2 Related Protein A1
MCL-1 Myeloid Cell Leukemia Sequence 1
Fas Tumor Necrosis Factor Receptor Superfamily, Member 6
RTK Receptor tyrosine kinase
PI3K Phosphatidylinositol-3 kinase
TNFα Tumor necrosis factor alpha
TNFR1 TNFα Receptor 1
TRADD TNFR1-associated death domain
TRAIL TNF-related apoptosis inducing ligand
FADD Fas-associated protein with death domain
NF-κB Nuclear factor kappa-light-chain-enhancer of activated B cells
MDM2 Mouse double minute 2 homolog
MOMP Mitochondrial outer membrane permeabilization
ER stress Endoplasmic reticulum stress
DISC Death-inducing signaling complex
FIP200 FAK family kinase-interacting protein of 200 kDa
ULK1 UNC-51-like kinase 1
IGF-1 Insulin-like growth factor-1
HER Human epidermal growth factor receptor
VEGFRs Vascular endothelial growth factor receptors
IRS Insulin receptor substrate
PtdIns(4,5)P2 Phosphatidylinositol 4,5-bisphosphate
PtdIns(3,4,5)P3 Phosphatidylinositol (3,4,5)-trisphosphate
PtdIns(3,4)P2 Phosphatidylinositol 3,4-bisphosphate
PTEN Phosphatase and tensin homolog
PDK1 3-Phosphoinositide-dependent protein kinase-1
PP2A Protein phosphatase 2
LKB1 Liver kinase B1
ERAD Endoplasmic-reticulum-associated protein degradation