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. 2017 Feb 10;18(2):368. doi: 10.3390/ijms18020368

Figure 1.

Figure 1

The impact of aging on mercuric chloride-induced acute kidney injury (AKI). Rats were challenged with 2 mg/kg mercuric chloride and AKI was assessed by serum creatinine. In the top panel, rats at different ages were challenged and harvested 1 or 4 days following challenge; In the bottom panel, 20 month (mon) old rats were challenged with mercuric chloride and serum creatinine was assessed 2, 7 or 10 days following injury. Each data point represents the mean + SEM of 3–4 animals, * indicates a significant difference from young control (4 mon).