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. 2017 Feb 10;18(2):373. doi: 10.3390/ijms18020373

Figure 5.

Figure 5

Effects of HCD + ESL on atherosclerotic lesion formation in the aortic sinus of LDLR−/− mice fed a Western diet for 12 weeks: (A) representative micrographs of an oil red O-stained cross-section of an aortic sinus (magnification, 40×) from each group are shown; (B) Quantification of the oil red O-stained aortic sinus lesional areas. Black lines are shown as mean lesion area; and (C) the percentage of oil red O-stained lesion areas in the whole aortic sinus from each group was performed by computer-associated morphometry and the results are presented in the graph. The results are shown as mean ± SD. # p < 0.01 vs. the chow diet group. * p < 0.05 and ** p < 0.01 vs. the HCD group. Chow diet, chow-fed group; HCD, high-cholesterol diet-fed group; HCD + ESL, 1% (wt/wt diet) ESL supplemented HCD-fed group.