Fig. 3.

Depression scores of high-, moderate, and low-risk children in the maltreatment and CC groups. There was a significant three-way interaction among maltreatment, genotype, and social supports in predicting children's depression scores (P < 0.0001). Maltreated children with the s/s genotype and low social supports had markedly elevated depression scores, ratings that were approximately twice as high as those of CCs with the same genotype and social support profile (high-risk CC, 15.0 ± 8.3; high-risk maltreated, 30.0 ±12.3). However, although the combination of the s/s genotype and low social supports was associated with very high depression scores in the maltreated cohort, maltreated children with only one of these risk factors had only modest increases in their depression scores compared with CCs (moderate-risk CC, 12.8 ± 8.8; moderate-risk maltreated, 15.3 ± 9.7).