Table 3.
Responses to treatment questions.
2010 |
2015 |
|||
---|---|---|---|---|
N | %a | N | %a | |
1. How many cycles before you operate? | ||||
Standard 3 cycles | 173 | 53.6 | 128 | 53.8 |
Standard 4 cycles | 21 | 6.5 | 7 | 2.9 |
Variable; depends on response | 135 | 41.8 | 101 | 42.5 |
6 cycles or more | 5 | 1.5 | 2 | 0.8 |
2. After NACT with a complete response, you: | ||||
LSC exploration, cytoreduction only if gross disease | 12 | 3.8 | 11 | 4.7 |
Ex-lap, cytoreduction if gross residual | 26 | 8.2 | 9 | 3.8 |
LSC exploration, TLH/BSO even in absence of gross diseaseb | 66 | 20.8 | 92 | 39.2 |
Ex lap with TAH/BSO even in absence of gross diseaseb | 225 | 70.8 | 111 | 47.2 |
Not undergo surgical exploration | 5 | 1.6 | 1 | 0.4 |
Other | 24 | 7.5 | 11 | 4.7 |
3. After NACT with gross residual on ID, you: | ||||
If optimally cytoreduced place a port and treat with at least 2 IP cycles | 136 | 42.2 | 98 | 42.1 |
If optimally cytoreduced continue IV chemo | 139 | 43.2 | 75 | 32.2 |
Switch IV treatment to _____ | 16 | 5 | 2 | 0.9 |
Treat with IP regardless of cytoreductive result | 1 | 0.3 | 4 | 1.7 |
Treat with more IV regardless of cytoreductive result | 59 | 18.3 | 45 | 19.3 |
4. After NACT with microscopic disease on ID, you: | ||||
At least 2 cycles of IP | 157 | 48.9 | 99 | 42.9 |
Continue with same type of IV | 164 | 51.5 | 118 | 51.1 |
Switch IV treatment to _____ | 12 | 3.7 | 7 | 3 |
Offer no treatment and start disease surveillance | 2 | 0.6 | 3 | 1.3 |
Key
LSC = laparoscopic; TLH = total laparoscopic hysterectomy; BSO = bilateral salpingo-oophorectomy; TAH = total abdominal hysterectomy; IV = intravenous; IP = intra-peritoneal.
Percentages are based on the number of participants responding to each question, some participants marked multiple answers.
denotes statistically significant difference between years p < 0.0001 by two-sample t-test.