Table 2.

Percent change of 18F-fluoromisonidazole (FMISO) metrics between imaging time points.

Patient #	1	2	3	4	Mean	Standard Deviation
Hypoxic Volume	−19.2	−97.1	−86.5	0	−50.75	48.25
Hypoxic Volume T/Bmean	−3.06	−18.2	5.78	NA	−5.16	10.23
Hypoxic Volume T/Bmax	−13.1	−31.1	−28.9	NA	−24.37	14.58
FLAIR Volume	−59.9	3.26	7.32	−14.1	−15.86	30.80
FLAIR T/Bmean	2.51	−22.6	−1.09	14.1	−1.77	15.32
FLAIR T/Bmax	−27.9	−46.7	−51.4	62.1	−15.98	53.03
Enhancing Volume	−80.4	−96.9	−95.8	−41.4	−78.63	25.93
Enhancing T/Bmean	34.1	−33.3	−1.92	11.5	2.60	28.17
Enhancing T/Bmax	−27.9	−46.7	−51.4	62.1	−15.98	53.03
Lesion rCBV	−22.0	−50.1	−46.2	−0.04	−30.5	17.3
Lesion rCBF	−18.4	−12.1	−0.04	−0.01	−0.22	0.08

Reference: NA, not applicable; T/B, tissue to background FMISO uptake ratio; max, maximum. Negative value represents decrease in percent change from baseline. Lesion rCBV and rCBF calculated at baseline (enhancing mass) and follow-up exam (reduced diffusion mass when present, or T2 hyperintense lesion when no reduced diffusion mass was present).