Table 4. Skin expression of Ki67 and pERK at cycle 1 day 15.

Median (range) percent of baseline	30 mg BID (n=4)	45 mg BID (n=22)	60 mg BID (n=7)	Total (N=33)
Ki67	44 (25–56)	33 (6–300)	31 (17–100)	33 (6–300)
pERK	88 (50–100)	66 (38–189)	59 (29–72)	64 (29–189)

Abbreviations: BID=twice daily.