Figure 2. Visualization of experimental virulence-linked essential genes.
Distribution of virulence-linked genes and growth-essential genes from experiments in CF sputum visualized across all mPA14 reactions (grey) using MetDraw. Reactions associated with virulence-linked genes (as defined by the Pseudomonas Genome Database) are highlighted in red, and reactions associated with genes essential to growth in synthetic cystic fibrosis sputum are shown in blue. Purple reactions are associated with both virulence and growth essentiality. All reactions and metabolites are labelled with unique identifiers referenced in the model, visible at high magnification and text-searchable.