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. 2017 Mar 9;12(3):e0173144. doi: 10.1371/journal.pone.0173144

Table 2. Influence of leptin SDS and SMA type on motor function.

MFM32 estimatedcoeff. [95%-CI] p-value(t-Test) SMA—globaltest (F-Test)
D1: standing Leptin SD 0.2 (-1.3–1.6) 0.799
position SMA II vs. I 3.2 (-1.6–8.1) 0.183
and transfers SMA III vs. I 56.6 (33.0–80.1) <0.001 <0.001
constant -0.3 (-8.1–7.5) 0.935
D2: axial and Leptin SD -3.6 (-7.5–0.3) 0.066
proximal SMA II vs. I 28.7 (8.3–49.1) 0.007
motor SMA III vs. I 67.8 (43.8–91.8) <0.001 <0.001
function constant 28.2 (3.0–53.4) 0.029
D3: distal Leptin SD -2.7 (-6.8–1.4) 0.184
motor SMA II vs. I 26.8 (-9.1–62.7) 0.137
function SMA III vs. I 67.4 (30.0–104.8) 0.001 <0.001
constant 31.0 (-9.6–71.6) 0.129
Total Leptin SD -1.9 (-4.2–0.3) 0.094
score SMA II vs. I 17.8 (2.4–33.3) 0.025
SMA III vs. I 62.7 (42.1–83.3) <0.001 <0.001
constant 17.4 (-0.7–35.5) 0.060

MFM32 = Motor Function Measurement32, vs. = versus; SD = Standard Deviation, coeff. = Coefficient; CI = Confidence Interval; SMA = spinal muscular atrophy