Table 1. Association of Th2-related molecules with clinical characteristics in 43 patients with OLP.
| Case (%) | CD11c+ cells (/HPF) | P-value | GATA3+ cells (/HPF) | P-value | |
|---|---|---|---|---|---|
| Age† | |||||
| ≤ 65 | 24 (55.8) | 88.7 ± 63.6 | 154.3 ± 115.3 | ||
| 65 < | 19 (54.2) | 99.3 ± 154.3 | N.S. | 187.8 ± 163.3 | N.S. |
| Gender† | |||||
| Male | 13 (30.2) | 92.6 ± 78.8 | 165.8 ± 143.7 | ||
| Female | 30 (69.8) | 93.8 ± 65.4 | N.S. | 170.6 ± 137.8 | N.S. |
| Affected site† | |||||
| Tongue | 4 (9.3) | 64.5 ± 88.1 | 74.4 ± 94.2 | ||
| Gingiva | 11 (25.6) | 69.9 ± 73.1 | 139.7 ± 159.8 | ||
| Buccal mucosa | 28 (65.1) | 106.8 ± 61.2 | N.S. | 194.2 ± 127.9 | N.S. |
| Clinical form † | |||||
| Reticular type | 20 (46.5) | 68.9 ± 62.4 | 114.4 ± 108.9 | ||
| Erosive type | 23 (53.5) | 114.7 ± 68.8 | 0.0243 | 216.8 ± 145.7 | 0.0374 |
| Viral infection† | |||||
| + | 6 (14.0) | 114.1 ± 75.8 | 202.3 ± 134.8 | ||
| − | 37 (86.0) | 94.6 ± 72.8 | N.S. | 171.4 ± 145.3 | N.S. |
| eGC formation† | |||||
| + | 5 (11.6) | 163.3 ± 80.0 | 331.6 ± 138.4 | ||
| − | 38 (88.4) | 84.2 ± 62.7 | 0.0488 | 147.8 ± 124.9 | 0.0131 |
| Resistance of steroid therap† | |||||
| + | 7 (16.3) | 77.1 ± 28.8 | 155.4 ± 107.5 | ||
| − | 36 (83.7) | 96.6 ± 74.7 | N.S. | 171.8 ± 144.9 | N.S. |
| Canceration† | |||||
| + | 4 (9.3) | 47.5 ± 17.0 | 90.4 ± 89.3 | ||
| − | 39 (90.7) | 98.1 ± 71.4 | N.S. | 177.2 ± 141.3 | N.S. |
Th2, T helper type 2; OLP, oral lichen planus; HPF, high-power field; eGC, ectopic germinal center; N.S., not significant.
† Mann-Whitney U-test and Wilcoxon signed-rank test.