Table 4. The incidence of tuberculosis in allogeneic hematopoietic stem cell transplantation recipients compared with the general population in Korea.
Transplant perioda | Duration of observation, patient-years | TB patients | SIR | 95% CI | P | |
---|---|---|---|---|---|---|
Observed n (%) | Expected n | |||||
Total (n = 845) | 3210.26 | 21 (2.49) | 2.30 | 9.10 | 5.59–14.79 | < 0.001 |
Jan. 2004-Mar. 2009 (n = 550) | 2341.64 | 16 (2.91) | 1.65 | 9.58 | 5.57–16.48 | < 0.001 |
Apr. 2009-Mar. 2011 (n = 295) | 868.62 | 5 (1.69) | 0.64 | 7.73 | 3.13–19.13 | < 0.001 |
TB, tuberculosis; SIR, standardized incidence ratio; CI, confidence interval.
a Starting April 2009, patients were given isoniazid prophylaxis based on interferon-γ release assay results.