Table 1. Trabecular bone variables: Ultra-distal femurs of stroke and control rats.
| Stroke | Control | p-value# | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Left / Paretic | Right / Non-paretic | STS % Diff^ | Left | Right | STS % Diff^ | Left | Right | STS | |
| N = 11 | N = 10 | N = 10 | N = 8 | ||||||
| BV/TV | 26.3 (21.9, 26.7) | 25.5 (23.4, 27.4) | 0.6 (-9.1, 8.2) | 26.2 (25.0, 28.1) | 25.3 (23.2, 28.1) | -2.4 (-7.8, 0.4) | 0.48 | 0.93 | 0.42 |
| TV | 13.8 (13.1, 14.3) | 13.9 (13.4, 14.4) | 3.5 (-1.7, 9.1) | 13.3 (13.0, 14.0) | 12.8 (12.6, 13.3) | -2.8 (-5.6, -1.0) | 0.48 | 0.01 | 0.02 |
| BV | 3.7 (2.8, 3.8) | 3.6 (3.3, 3.9) | 2.9 (-9.8, 16.5) | 3.6 (3.3, 3.8) | 3.4 (3.0, 3.7) | -7.6 (-12.9, -2.4) | 0.93 | 0.48 | 0.16 |
| vBMD | 304.9 (257.5, 313.6) | 295.7 (273.8, 315.5) | -1.6 (-8.7, 6.4) | 304.2 (290.5, 325.7) | 297.2 (275.2, 329.6) | -2.2 (-6.7, 0.4) | 0.53 | 0.72 | 0.66 |
| TMD | 905.8 (897.4, 916.5) | 892.3 (888.7, 895.5) | -1.5 (-3.0, 0.4) | 909.6 (903.3, 917.0) | 907.5 (900.9, 911.6) | -0.7 (-1.3, 0.2) | 0.80 | 0.03 | 0.13 |
| Conn. D | 211.4 (177.8, 227.1) | 194.1 (182.9, 230.0) | 1.4 (-8.5, 7.6) | 210.6 (188.4, 234.4) | 206.0 (195.9, 226.2) | -5.2 (-9.6, 8.8) | 0.59 | 0.86 | 0.59 |
| SMI | 1.33 (1.26, 1.55) | 1.33 (1.19, 1.42) | -7.1 (-11.3, 9.0) | 1.3 (1.2, 1.4) | 1.4 (1.3, 1.6) | 4.4 (0.6, 13.7) | 0.86 | 0.37 | 0.25 |
| Tb. N | 4.8 (4.1, 5.1) | 4.8 (4.6, 5.0) | 1.5 (-1.7, 11.1) | 4.9 (4.7, 5.2) | 4.8 (4.6, 5.1) | -0.9 (-7.5, 3.6) | 0.25 | 1.0 | 0.29 |
| Tb. Th | 67.6 (66.8, 6.99) | 66.7 (64.9, 68.2) | -2.2 (-4.9, 2.1) | 68.9 (68.2, 69.9) | 68.7 (66.2, 72.3) | -0.9 (-2.1, 2.1) | 0.42 | 0.25 | 0.53 |
| Tb. Sp | 0.19 (0.18, 0.24) | 0.19 (0.18, 0.20) | -0.9 (-15.0, 1.3) | 0.187 (0.176, 0.199) | 0.192 (0.179, 0.205) | 1.8 (-4.7, 8.1) | 0.29 | 1.0 | 0.25 |
Note. Median values (IQR) presented.
^ Side-to-side % difference; calculated [(right leg–left leg)/ left leg] x 100
#Between-group comparison: Wilcoxon rank-sum test
vBMD = volumetric bone mineral density, mg HA/cm3; BV = Bone volume, mm3; BV/TV = Bone volume fraction, %; Conn. D = Connective density, 1/mm; TMD = Tissue mineral density, mg HA/cm3; SMI = Structural model index (0 = parallel plates, 3 = cylindrical rods); Tb. N = Trabecular number, 1/mm; Tb. Th = Trabecular thickness, μm; Tb Sp = Trabecular separation, mm; TV = Total volume, mm3