Table 3. Bone turnover markers in rats: Percentage change from baseline.
Stroke | Control | p-value^ | ||
---|---|---|---|---|
Median (IQR) | Median (IQR) | |||
CTX, % | ||||
Day 7 | -7.1 (-19.1, 24.7) n = 8 | 1.3 (-27.1, 24.0) n = 8 | 0.46 | |
Day 27 | 4.9 (-5.7, 30.5) n = 9 | 0.7 (-34.2, 27.4) n = 7 | 0.79 | |
P1NP, % | ||||
Day 7 | -44.1 (-58.8,-26.1) n = 6 | -23.8 (-35.7,-14.5) n = 6 | 0.42 | |
Day 27 | -24.5 (-34.1,-10.5) n = 6^^ | -0.8 (-3.4, 43.1) n = 5 | 0.41 |
CTX = Degradation products of C-terminal telopeptides of type 1 collagen, bone resorption marker. P1NP = N-terminal propeptide of type 1 procollagen, bone formation marker
^Wilcoxon rank-sum comparison between stroke and control animals
^^One-sample median test compared to baseline value, p = 0.046.