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. 2017 Mar 9;12(3):e0173450. doi: 10.1371/journal.pone.0173450

Table 1. Demographic characteristics and prevalence of psychotropic use in different university hospital districts in 2005 and 2011.

Data are given as n (%) unless otherwise indicated.

2005 2011 P for temporal change
N (n eligible*) N (n eligible*)
Age, mean (SD)
Helsinki 2,126 (2,104) 79.5 (6.9) 6,868 (6,614) 80.4 (7.6) <0.001
Kuopio 1,673 (1,654) 79.3 (6.8) 4,790 (4,612) 80.3 (6.9) <0.001
Oulu 1,350 (1,342) 78.9 (6.5) 3,117 (3,054) 80.3 (7.1) <0.001
Tampere 1,961 (1,942) 79.4 (6.7) 5,013 (4,820) 80.6 (7.1) <0.001
Turku 1,410 (1,397) 79.9 (6.5) 3,249 (3,159) 81.1 (7.1) <0.001
P for regional difference 0.002 <0.001
Sex, women
Helsinki 2,126 (2,104) 1,398 (66.4) 6,868 (6,614) 4,314 (65.2) 0.31
Kuopio 1,673 (1,654) 1,055 (63.8) 4,790 (4,612) 2,947 (63.9) 0.93
Oulu 1,350 (1,342) 839 (62.5) 3,117 (3,054) 1,924 (63.0) 0.76
Tampere 1,961 (1,942) 1,269 (65.4) 5,013 (4,820) 3,065 (63.6) 0.17
Turku 1,410 (1,397) 933 (66.8) 3,249 (3,159) 2,066 (65.4) 0.36
P for regional difference 0.07 0.10
Antidementia medication use
Helsinki 2,126 (2,104) 1,205 (57.3) 6,868 (6,614) 4,867 (74.6) <0.001
Kuopio 1,673 (1,654) 1, 055 (63.8) 4,790 (4,612) 3,596 (78.0) <0.001
Oulu 1,350 (1,342) 853 (63.6) 3,117 (3,054) 2,348 (76.9) <0.001
Tampere 1,961 (1,942) 1,260 (64.9) 5,013 (4,820) 3,690 (76.6) <0.001
Turku 1,410 (1,397) 780 (55.8) 3,249 (3,159) 2,317 (73.4) <0.001
P for regional difference <0.001 <0.001
Any psychotropic, prevalent use
Helsinki 2,126 (2,104) 1,067 (50.7) 6,868 (6,614) 3,064 (46.3) <0.001
Kuopio 1,673 (1,654) 767 (46.4) 4,790 (4,612) 2,076 (45.0) 0.34
Oulu 1,350 (1,342) 600 (44.7) 3,117 (3,054) 1,377 (45.1) 0.82
Tampere 1,961 (1,942) 952 (49.0) 5,013 (4,820) 2,292 (47.6) 0.27
Turku 1,410 (1,397) 690 (49.4) 3,249 (3,159) 1,512 (47.9) 0.34
P for regional difference 0.004 0.027
Antipsychotics, prevalent use
Helsinki 2,126 (2,104) 341 (16.2) 6,868 (6,614) 1,043 (15.8) 0.63
Kuopio 1,673 (1,654) 303 (18.3) 4,790 (4,612) 789 (17.1) 0.27
Oulu 1,350 (1,342) 173 (12.9) 3,117 (3,054) 490 (16.0) 0.007
Tampere 1,961 (1,942) 301 (15.5) 5,013 (4,820) 820 (17.0) 0.13
Turku 1,410 (1,397) 224 (16.0) 3,249 (3,159) 554 (17.5) 0.21
P for regional difference 0.002 0.12
Antidepressants, prevalent use
Helsinki 2,126 (2,104) 595 (28.3) 6,868 (6,614) 1,775 (26.8) 0.20
Kuopio 1,673 (1,654) 368 (22.3) 4,790 (4,612) 1,031 (22.4) 0.93
Oulu 1,350 (1,342) 316 (23.6) 3,117 (3,054) 693 (22.7) 0.54
Tampere 1,961 (1,942) 491 (25.3) 5,013 (4,820) 1,192 (24.7) 0.63
Turku 1,410 (1,397) 368 (26.3) 3,249 (3,159) 768 (24.3) 0.14
P for regional difference <0.001 <0.001
BZDR, prevalent use
Helsinki 2,126 (2,104) 596 (28.3) 6,868 (6,614) 1,535 (23.2) <0.001
Kuopio 1,673 (1,654) 433 (26.2) 4,790 (4,612) 1,038 (22.5) 0.003
Oulu 1,350 (1,342) 376 (28.0) 3,117 (3,054) 731 (23.9) 0.004
Tampere 1,961 (1,942) 604 (31.1) 5,013 (4,820) 1,202 (24.9) <0.001
Turku 1,410 (1,397) 399 (28.6) 3,249 (3,159) 770 (24.4) 0.003
P for regional difference 0.027 0.050

*AD diagnosis not more than one year ago and not hospitalised/institutionalised for the entire assessment period