Table 2. Clinical features of papillary or follicular thyroid cancer with bone metastasis in thyroid cancer mortality or non-cancer mortality.
| Clinical Characteristic | All Patients | Cancer Mortality vs. Non-cancer Mortality | P value | |
|---|---|---|---|---|
| Cancer Mortality | Non-cancer Mortality | |||
| Patient number | 131 (100.0) | 88 (67.2) | 43 (32.8) | |
| Group A | 90 (68.7) | 69 (76.7%) | 21 (23.3%) | 0.001 |
| Group B | 41 (31.3) | 19 (46.3%) | 22 (53.7%) | |
| Gender, Female | 94 (71.8) | 68 (77.3) | 26 (60.5) | 0.045 |
| Age at diagnosis (year) | 57.4 ± 15.0 | 60.5 ± 13.1 | 51.0 ± 16.7 | 0.001 |
| Mean tumor size (cm) | 4.1 ± 2. | 4.7 ± 3.3 | 3.1 ± 1.7 | 0.011 |
| Median post-operative serum Tg level after 1 month (ng/mL) | 300 | 472 | 81.8 | 0.300 |
| (range) | (0.0–141970.0) | (1.4–141970.0) | (0.0–61845.0) | |
| Multifocality | 15 (11.5) | 9 (10.2) | 6 (14.0) | 0.529 |
| Operative method | ||||
| Total thyroidectomy | 87 (66.4) | 56 (63.6) | 31 (72.1) | 0.336 |
| Less than total thyroidectomy | 44 (33.6) | 32 (36.4) | 12 (27.9) | |
| Histology | ||||
| Papillary | 79 (60.3) | 43 (54.4) | 36 (45.6) | <0.001 |
| Follicular | 52 (39.7) | 45 (86.5) | 7 (13.5) | |
| TNM stage | ||||
| Stage I | 10 (7.6) | 2 (2.3) | 8 (18.6) | 0.002 |
| Stage II | 19 (14.5) | 10 (11.4) | 9 (20.9) | |
| Stage III | 8 (6.1) | 5 (5.7) | 3 (7.0) | |
| Stage IV | 94 (71.8) | 71 (80.7) | 23 (53.5) | |
| Follow-up period (year) | 8.4 ± 7.0 | 6.6 ± 5.3 | 11.9 ± 8.6 | <0.001 |
| Post-operative 131I accumulative dose (mCi) | 451.4 ± 480.8 | 433.8 ± 449.5 | 491.1 ± 543.2 | 0.612 |
| Radiation therapy | 68 (51.9) | 54 (61.4) | 14 (32.6) | 0.002 |
| 131I avid lesion | 98 (74.8) | 63 (71.6) | 35 (81.4) | 0.225 |
| 2nd primary cancer | 10 (7.6) | 5 (5.7) | 5 (11.6) | 0.229 |
| Brain metastasis | 8 (6.1) | 8 (9.1) | - | 0.041 |
Number (%)