Figure 3.

Four nucleotide variants that show statistically significant differences in frequency between presbycusis and control subjects.

Notes: The panels show comparisons of each nucleotide variant with the rCRS using Codon Code Aligner. The upper sequences represent rCRS and the lower sequences are those amplified from study participants. The black lines and squares indicate the nucleotide positions and alternations.

Abbreviations: rCRS, revised Cambridge Reference Sequence; mtDNA, mitochondrial DNA.