Table 2. Planktonic and biofilm bacteria sensitivity to FLIP7 and reference antibiotics (TTC assay).

Strain	Planktonic bacteria MIC, μg/mL	Biofilm bacteria MBIC90, μg/mL	P*	MBIC90/ MIC ratio
E. coli ATCC 25922
FLIP7	500 ± 0.00	1667 ± 88	<0.001	3.3
Cefotaxime	0.125 ± 0.00	3 ± 0.7	0.005	24
Meropenem	0.03 ± 0.00	0.9 ± 0.3	<0.001	30
Polymyxin	0.5 ± 0.00	12.3 ± 0.3	<0.001	24.6
E. coli NCTC 13353
FLIP7	250 ± 0.00	2567 ± 617	0.02	10.3
Meropenem	0.06 ± 0.00	2.3 ± 0.9	0.073	38.3
Polymyxin	1.3 ± 0.3	52 ± 14	0.022	40.0
S. aureus 203
FLIP7	667 ± 167	1543 ± 137	0.015	2.3
Meropenem	0.03 ± 0.005	>5		>167
Vancomycin	0.5 ± 0.00	25± 13	0.134	50
S. aureus 73.1
FLIP7	8000 ± 0.00	7333 ± 167	0.016	0.9
Meropenem	0.08 ± 0.00	0.29 ± 0.08	0.06	3.6
A. baumannii 28
FLIP7	125 ± 0.00	6433 ± 1417	0.011	51
Polymyxin B	0.4 ± 0.1	267 ± 67	0.016	667
A. baumannii 143
FLIP7	125 ± 0.00	3767 ± 33	<0.001	30
Polymyxin B	0.25 ± 0.00	>20		>80
A. baumannii 149.2
FLIP7	416 ± 83	7600 ± 306	<0.001	18
Meropenem	0.5 ± 0.00	1.5 ± 0.06	<0.001	3
Polymyxin B	0.7 ± 0.2	30.3 ±6.2	0.009	43

*Each test consisted of 3 independent measurements