Table 2. Genotype, allele, and haplotype frequencies of DBP gene variants in PCOS and control women.
| SNP | Controls n (%) | PCOS n (%) | p |
|---|---|---|---|
| rs2282679 | |||
| AA | 61 (61%) | 103 (55%) | 0.360 |
| AC | 33 (33%) | 65 (35%) | |
| CC | 6 (6%) | 20 (10%) | |
| A | 155 (77%) | 271 (72%) | 0.159 |
| C | 45 (23%) | 105 (27%) | |
| rs4588 | |||
| CC | 61 (61%) | 104 (55%) | 0.479 |
| CA | 32 (32%) | 66 (35%) | |
| AA | 7 (7%) | 20 (10%) | |
| C | 154 (77%) | 274 (72%) | 0.203 |
| A | 46 (23%) | 106 (28%) | |
| rs7041 | |||
| TT | 24 (24%) | 47 (25%) | 0.911 |
| TG | 45 (45%) | 88 (47%) | |
| GG | 31 (31%) | 54 (28%) | |
| T | 93 (47%) | 182 (48%) | 0.706 |
| G | 107 (53%) | 196 (52%) | |
| Haplotypes | |||
| CG CG + CT CG | 54 (54%) | 94 (49.3%) | 0.740 |
| CG AT + CT CT | 29 (29%) | 61 (31.9%) | |
| CT AT + AT AT | 17 (17%) | 36 (18.8%) |
Data are expressed as percentage. p value by Pearson’s χ2 test. The rs4588-rs7041 haplotype is grouped by presence of the risk haplotype.