Table 2. FCN3 genotype, allele and haplotype frequencies (%).
| dbSNP | Controls | Leprosy per se | Lepromatous | Non-lepromatous | |
|---|---|---|---|---|---|
| rs532781899 | N = 245 | N = 190 | N = 144 | N = 53 | |
| Genotype | g.1637C/1637C | 96.0 | 95.0 | 95.0 | 94.0 |
| g.1637del/1637C | 4.0 | 5.0 | 5.0 | 6.0 | |
| n = 490 | n = 380 | n = 228 | n = 106 | ||
| Allele | g.1637C | 97.8 | 97.6 | 97.4 | 97.2 |
| g.1637del | 2.2 | 2.4 | 2.6 | 2.8 | |
| rs28362807 | N = 146 | N = 149 | N = 87 | N = 42 | |
| Genotype | g.3524_3532del/3524_3532del | 51.0 | 52.0 | 49.0 | 55.0 |
| g.3524_3532del/3524_3532ins | 42.0 | 42.0 | 43.0 | 43.0 | |
| g.3524_3532ins/3524_3532ins | 7.0 | 6.0 | 8.0 | 2.0 | |
| n = 292 | n = 298 | n = 174 | n = 84 | ||
| Allele | g.3524_3532del | 72.3 | 72.8 | 71 | 76.2 |
| g.3524_3532ins | 27.7 | 27.2 | 29 | 23.8 | |
| rs4494157 | N = 146 | N = 149 | N = 87 | N = 42 | |
| Genotype | g.4473C/4473C | 55.0 | 58.0 | 53.0 | 64.0 |
| g.4473C/4473A | 40.0 | 38.0 | 40.0 | 36.0 | |
| g.4473A/4473A | 4.0 | 5.0 | 7.0 | - | |
| n = 292 | n = 298 | n = 174 | n = 84 | ||
| Allele | g.4473C | 75.7 | 76.5 | 73 | 82.1 |
| g.4473A | 24.3 | 23.5 | 27 | 17.9 | |
| Phylogenetic nomenclature | Haplotype | n = 292 | n = 298 | n = 174 | n = 84 |
| *2ª | C del C | 71.6 | 71.1 | 69 | 73.8 |
| *2B1 | C ins A | 24.3 | 23.5 | 27 | 17.9 |
| *1 | C ins C | 2.74 | 3.7 | 2.3 | 5.9 |
| *2B2.2A | del del C | 0.68 | 1.7 | 1.7 | 2.4 |
| *2B2 | del ins C | 0.68 | - | - | - |
N: number of individuals. n: number of chromosomes. dbSNP: nomenclature according to the Single Nucleotide Polymorphism database. Unspecified leprosy patients were excluding when clinical forms of the disease were compared.