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. Author manuscript; available in PMC: 2018 Mar 1.
Published in final edited form as: Alzheimers Dement. 2016 Sep 30;13(3):205–216. doi: 10.1016/j.jalz.2016.08.005

Figure 4. Biomarkers vs age.

Figure 4

Scatter plots of each biomarker versus age among all MCSA CN individuals with box plots of the cognitively impaired group shown for reference. The horizontal lines indicate cut-points chosen from the five methods. The colors used were as follows: reliable worsening (RW), blue (only in panel A); specificity (Spec.), green; sensitivity (Sens.), red; accuracy of cognitively impaired versus young CN (Acc-Young), orange; accuracy of cognitively impaired versus matched CN (Acc-Matched), purple. Using each of these five cut-point methods, we then label individuals as positive or negative and show the percent positive as estimated from logistic regression models. For amyloid PET (panel A), values are shown in both SUVR and centiloid units.