Skip to main content
. Author manuscript; available in PMC: 2018 Feb 1.
Published in final edited form as: Mech Dev. 2017 Jan 10;143:32–41. doi: 10.1016/j.mod.2017.01.003

Figure 9. Wnt signaling cell-autonomously inhibits PM specification.

Figure 9

(A) Schematic of blastula cell transplantation method. (B, C) Representative donor cells that incorporated into the heart and PMs at 72 hpf. (D) Graph indicating the frequency of donor cell contribution in embryos to the heart and the PMs. WT donor cells ->WT host transplants n=240. Tcf7l depleted donor cells ->WT host em bryos n=221. Tcf7l1 depleted donor cells contributed significantly more to the cardiomyocytes and less frequently to the PMs compared to WT donors. Images are lateral views with anterior leftwards. Scale bar indicates 100 µm.